Trypanocidal and Leishmanicidal Properties of Substitution-Containing Chalcones
نویسندگان
چکیده
منابع مشابه
Trypanocidal and leishmanicidal properties of substitution-containing chalcones.
Ten chalcones were synthesized and tested as potential leishmanicidal and trypanocidal agents. All tested compounds caused concentration-dependent inhibition of the in vitro growth of Leishmania braziliensis and Trypanosoma cruzi with no significant toxic effect towards host macrophages. Our results show that the positions of the substituents seem to be critical for their antiprotozoal activities.
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2003
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.47.4.1449-1451.2003